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Table 1.1 summarizes the number of dental research publications combined with research on the brain and neuroimaging, according to a PubMed‐based survey. The trend of publication of dental research related to neuroimaging was strikingly similar to that related to the brain. Before 1970, only a few publications were found in these fields. In contrast, after the 1990s, the percentage of these studies showed a pronounced increase. Notably, this trend in publication can be compared with the dental research related to neuroscience in general, as recently reported by Iwata and Sessle (2019). In terms of brain and neuroimaging research, almost half of the dental research on brain and neuroimaging was published last decade (2011–2020) (Table 1.1). This trend is very different from the general field of neuroscience. It is also noteworthy that more than 90% of the dental research on neuroimaging was published after the mid‐1990s, about the same time when functional magnetic resonance imaging (fMRI) came into practice (Bandettini 2012). The trend reflects that technological innovation of biomedical imaging may facilitate cross‐disciplinary research on dentistry and the brain.

Table 1.1 Trends of the academic publication^a in dental research related to brain and neuroimaging.

Period	Dentistry + Brain	Dentistry + Neuroimaging
No. of articles	Percentage	No. of articles	Percentage
2011–2020	10004	49	391	65
2001–2010	5119	25	152	25
1991–2000	2773	14	61	10
1981–1990	1719	8	2	0
1971–1980	631	3	0	0
1961–1970	145	1	0	0
1951–1960	53	0	0	0
before 1951	11	0	0	0

^a The number of articles was surveyed using PubMed with the following combination of keywords: ‘tooth[mesh] OR oral[mesh] OR dental[mesh] OR dentistry[mesh] OR teeth[tiab] OR tooth[tiab] OR oral[tiab] OR dental[tiab] OR dentistry[tiab]’ in conjunction with ‘brain[tiab]’ and ‘neuroimaging[tiab]’ for ‘Dentistry + Brain’ and ‘Dentistry + Neuroimaging’, respectively.