Читать книгу Medical Statistics - David Machin - Страница 20

It has been emphasised that design deserves as much consideration as analysis, and a statistician can provide advice on design. In a clinical trial, for example, what is known as a double‐blind randomised design is nearly always preferable (see Chapter 15), but not always achievable. If the treatment is an intervention, such as a surgical procedure, it might be impossible to prevent individuals knowing which treatment they are receiving but it should be possible to shield their assessors from knowing. We also discuss methods of randomisation and other design issues in Chapter 15.