Читать книгу Randomised Clinical Trials - David Machin - Страница 92
Example 3.9 Protocol SQNP01 (1997): Standard radiotherapy versus concurrent chemo‐radiotherapy followed by adjuvant chemotherapy for locally advanced (non‐metastatic) nasopharyngeal cancer
Оглавление| Therapy | Dose | Route | Days |
| CisDDP | i) 25 mg/m2/day for 4 days | IV over 6–8 hours | 1–4 (Week 1) |
| 22–25 (Week 4) | |||
| 43–46 (Week 7) | |||
| ii) Alternatively, 30/30/40 mg/m2/day for 3 days, if patient starts RT on a Wednesday and only for the first cycle | 1–3 (Week 1) | ||
| 22–25 (Week 4) | |||
| 43–46 (Week 7) | |||
| RT | 200 cGy/day | Mega‐voltage with or without electrons | 35 daily treatments |
