Читать книгу Primary Care for COMLEX Level 1 - Dr. Jahan Eftekar - Страница 48
PATHOLOGY
Оглавление•Leukemia are more prevalent in kids
•Hodgkin’s occurs in young kids.
•All nephrotic syndromes show glomerular damage EXCEPT lipoid Nephrosis.
•All lipid storage diseases have more predilection for brain and liver tissues EXCEPT Fabry’s which affects Renal and dermal tissues.
•Anderson’s disease is the only glycogen storage disease that lacks hepatomegaly
•All Glycogen storage diseases are associated with an increased storage of glycogen in liver or muscle EXCEPT Andersen’s (Type IV) disease (That lacks branching enzyme system which is required for glycogen synthesis from glucose).
•Most carcinomas of the GI are prominent in men EXCEPT gall bladder which is more prominent in women.
•All genetic renal diseases are autosomal recessive EXCEPT for Adult Polycystic Disease.
•All coagulation factors are made by the liver EXCEPT coagulation factor VIII (that is secreted/associated with the endothelial cells). Note that the integrity of VIII—made by the liver, is dependent upon vWF that is secreted by the endothelium.
•Cancers of esophagus tend to be of squamous epithelial origin EXCEPT for Barrett's CA.
•All connective tissue (collagen diseases) are more prevalent in females except polyarteritis nodosa.
•All Aminoacidopathies cause mental retardation EXCEPT tyrosinemia that causes pigment-related anomalies, liver cirrhosis and renal acidosis.
•All porphria are more common in females EXCEPT cutanea tarda.
•All mucopolysaccharidoses are autosomal recessive EXCEPT Hunter’s disease.
•All types of Hodgkin’s are more prevalent in young men, EXCEPT nodular sclerotic types
•If it is an endocrine deficiency it is most likely due to an autoimmune ailment
•If it is endocrine excess it is most likely due to a benign adenoma EXCEPT hyperprolactinemia that is due to dopamine deficiency.