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Liquid/liquid chromatography (LLC)

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The stationary phase and the mobile phase are both liquids. The stationary phase is most often a polymer fixed on an inert support, generally by grafting active species with covalent bonds, ensuring a long lifespan for these columns. The separation relies upon the partition coefficient of the solutes between the two phases (a phenomenon comparable to a liquid–liquid extraction in a separatory funnel, a well‐known process in laboratories). This category also includes centrifugal partition chromatography, which is used in preparative chromatography.

Chemical Analysis

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