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Preface

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The successful practice of Medicine is predicated upon the ability to use drugs safely and effectively. This ability can be difficult to acquire and needs to be maintained as the range of drugs available to alleviate symptoms and to treat disease is constantly growing. As our understanding of the genome, and of the molecular basis of disease has increased, the development of new drugs with novel mechanisms of action has accelerated, expanding the available pharmacopeia for clinicians from all disciplines and therapeutic areas.

As our knowledge evolves, so must our textbooks. This tenth edition of Lecture Notes in Clinical Pharmacology has been extensively revised, refreshed and updated to provide the reader with an authoritative and modern insight into the use of drugs in the treatment of human disease.

Although the range of drugs available has expanded hugely since the first edition of this book was published almost 40 years ago, in preparing this text we continue to be guided by the principles established in that edition: we have retained a clear focus on practical elements and clinical relevance throughout, in order to maximise utility for the student or practising clinician. Rather than indulgence in exhaustive detail, we have chosen to set out concisely and with clarity the principles which guide clinicians in their choices and have made use of illustrative examples from scenarios commonly encountered on wards and in clinics. In doing so, we hope to provide the reader with an accessible and helpful guide which imparts a useful understanding of not only how, but also when to use drugs.

Gerard A. McKay

Neil D. Ritchie

Matthew R. Walters

Glasgow

October 2020

Clinical Pharmacology and Therapeutics

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