Читать книгу Organofluorine Chemistry - Группа авторов - Страница 36

We have reviewed developments in perfluoroalkylation reactions with perfluorocarboxylic acids and anhydrides as perfluoroalkylating reagents. Early work tended to focus on methodologies for the generation of reactive species, such as perfluoroalkyl radicals and perfluoroalkyl metal species, and their reactivities. More recent reports have dealt with precise control of the reactivity of reactive intermediates and efficient production of perfluoroalkylated molecules containing important skeletons as candidate pharmaceuticals and functional materials. Based on the ready availability of the perfluoroalkyl sources and the high synthetic utility of recently reported reactions, we consider that perfluorocarboxylic acids and anhydrides will become the first choice of perfluoroalkylating reagents for practical organic syntheses in the near future.