Читать книгу Methodologies in Amine Synthesis - Группа авторов - Страница 43

The last pattern for the radical‐involved C—N bond formation is the cross‐coupling of C‐ and N‐radicals, which is relatively undeveloped compared with the aforementioned two pathways, presumably because of the challenge to provide an appropriate environment for the simultaneous generation of both C‐ and N‐radicals. Moreover, the generated C‐ and N‐radical in the same system are supposed to obey to the principle of persistent radical effect (PRE) to furnish the desired C–N cross‐coupling product rather than the homocoupling ones.