Читать книгу Blood and Marrow Transplantation Long Term Management - Группа авторов - Страница 101

Many novel developments in management or prognostication of late effects of HCT have occurred, most notably of which include machine learning methods for GVHD predictions [72], inheritable risk for cardiotoxicity [73], and the effect of microbiome on late infectious complications [74].

With the improvement in the survival of allogeneic‐HCT patients [75], it is predicted that more late complications will be identified in the HCT recipients. Evidence‐based surveillance strategies for early recognition and prompt management of these late effects are best undertaken in multidisciplinary long‐term follow‐up. Future allogeneic HCT studies should focus on assessing long‐term outcomes by obtaining pretransplant risk factors for late effects, translational studies utilizing biomarkers, and follow‐through of the late and very late complications in a prospective fashion.