Читать книгу Blood and Marrow Transplantation Long Term Management - Группа авторов - Страница 94

Infections (particularly aspergillosis, HHV‐6, CMV, respiratory syncytial virus, influenza, and parainfluenza viruses), BOS (bronchiolitis obliterans syndrome), COP (cryptogenic organizing pneumonia) and pulmonary thromboembolism are the main pulmonary late effects of allogeneic‐HCT. BOS occurs in 2–14% of allogeneic‐HCT recipients [48]. Smoking, TBI, chemotherapy (particularly busulfan), preexisting lung disease, and early HCT pulmonary complications are known risk factors. Surveillance strategies with history, examinations and pulmonary function tests at regular intervals post‐HCT may help to diagnose BOS in its early stage. This topic is further discussed elsewhere.