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The use of prior nephrotoxic medications (e.g., cisplatin, foscavir, vancomycin etc.) and CNI therapy for the prevention or treatment of GVHD predisposes to the development of chronic kidney disease [37] which can manifest as either glomerulonephritis or interstitial fibrosis. Among chronic infections, CMV and adenovirus are known offenders, and a search for these organisms is warranted if renal infections are suspected.