Читать книгу Blood and Marrow Transplantation Long Term Management - Группа авторов - Страница 151

Chronic obstructive pulmonary disease (COPD) with reduced FEV₁/FVC and FEV₁ develops in up to 20% of long‐term survivors after HSCT. The pathogenesis is not well understood, but cGVHD, TBI, hypo‐gammaglobulinemia, GVHD prophylaxis with methotrexate, and infections have been described as risk factors [17] and review in Barker et al. [35].