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The Gonads

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Abnormally formed gonads are at risk of developing malignancies. This risk varies with the nature of the DSD. The highest risks are mostly of mixed gonadal dysgenesis, pure gonadal dysgenesis, and Frasier and Drash syndromes. The tumor, when it arises, develops from the testicular contingent of the gonads [32]. These abnormal gonads can be either brought down into the scrotum to allow close follow-up or removed. Many patients will require some form of hormonal supplementation at the age of puberty and beyond if gonadectomy is elected.

Handbook of Clinical Gender Medicine

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