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Hydrogen (H₂) is the lightest and most abundant of chemical elements, constituting nearly 90% of the universe’s elemental mass. In contrast, earth’s atmosphere contains less that 1 ppm of hydrogen. H₂ is known to be highly flammable and to violently react with oxidizing elements as typified by the 1937 Hindenberg Zeppelin disaster. Therefore, the use of H₂ as a therapeutic agent is not intuitively obvious. However, recent evidence indicates that inhaled H₂ gas has antioxidant and anti-apoptotic properties that can protect organs from ischemia-reperfusion-induced injury by selectively scavenging detrimental ROS. The mechanism of action of inhaled H₂ gas in these models involves its ability to prevent oxidative damage, as indicated by decreased nucleic acid oxidation and lipid peroxidation [15, 16]. H₂-rich liquid such as H₂ water represents a novel and easily translatable method of delivery of molecular H₂. H₂ water may be of potential therapeutic value in the treatment of oxidative stress-induced pathologies as well as inhaling H₂ gas [17, 18]. A clinical trial in type 2 diabetic patients given supplemental H₂ water led to improved lipid and glucose metabolism compared to controls [19].