Читать книгу Protein in Neonatal and Infant Nutrition: Recent Updates - Группа авторов - Страница 37

One prospective open, randomized clinical study compared the clinical tolerance of a hydrolyzed rice protein formula (HRPF) with a CMP eHF in 92 infants (mean age 4.3 months, range 1.1-10.1 months) with IgE-mediated CMA. The HRPF was well tolerated in all infants tested, and measurement of IgE levels towards CMP during the study showed no significant differences between the two formula groups. During the follow-up (at 3, 6, 12 and 24 months), children receiving HRPF showed similar growth and development of clinical tolerance to those receiving an eHF [49].

A new extensively HRPF (eHRPF) for infants was tested in 40 infants with CMA confirmed by food challenge. All infants tolerated the eHRPF (according to a symptom-based score and growth parameters) and symptoms significantly decreased in the first month of the eHRPF intervention [50, 51].

However, the content of arsenic in rice infant formula needs to be controlled [52], and further studies with short- and long-term data on allergic reactions, nutritional adequacy and safety are needed.