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Fluid Overload

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Recent studies demonstrated the relevant role of fluid overload as AKI determinant. Indeed, a number of retrospective analysis investigating critically ill patients correlated central venous pressure and fluid overload with mortality and worse renal outcomes [25]. All these findings have been recently confirmed by a large multicenter, prospective, observational trial: authors found that the severity and speed of fluid accumulation are independent risk factors for ICU mortality [26].

Current Perspectives in Kidney Diseases

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