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Current Concepts in Movement Disorder Management
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Progress in Neurological Surgery
Current Concepts in Movement Disorder Management
Страница 5
Contents
Series Editor’s Note
Preface
Страница 9
The History of Movement Disorder Brain Surgery
Abstract
The Pre Stereotactic Era
The Early Era of Stereotactic Brain Surgery
The Era of Spreading Stereotactic Techniques
The Era of Decline of Stereotactic Surgery
The Early Transplant Era
The Era of Advanced Stereotactic Imaging and Mapping
The Deep Brain Stimulation Era
The Era of Radiosurgery
The Evolution of Frameless Technologies and Intraoperative MRI
Conclusions
References
Страница 23
Pathophysiologic Basis of Movement Disorders
Abstract
Introduction
Relevant Brain Circuit Anatomy
Basal Ganglia Circuits
Cerebellar Circuits and Cerebello-Basal Ganglia Interactions
Parkinson’s Disease
Rate Model of Basal Ganglia Disorders
Pattern Changes in Parkinsonism
Extrastriatal Dopamine Loss
Other Structural Changes Contributing to the Motor Disturbance in PD
Dystonia
Basal Ganglia Dysfunction in Dystonia
Cerebellar and Cortical Abnormalities in Dystonia
Essential Tremor
Conclusions
References
Страница 41
Clinical Presentation and Prognosis of Common Movement Disorders
Abstract
Introduction
Parkinsonian Syndromes
Parkinson Disease
Secondary Parkinsonism
Atypical Parkinsonian Syndromes
Tremor
Essential Tremor
Other Causes of Action Tremor
Dystonia
Tics and Tourette Syndrome
Conclusion
References
Страница 56
Medical Management of Movement Disorders
Abstract
Parkinson’s Disease
Early Stage
MAO-B Inhibitors
DAs
Levodopa
Advanced Stage
COMT Inhibitors
Apomorphine
Levodopa/Carbidopa Intestinal Gel
Essential Tremor
Beta-Blockers
Anticonvulsants and Benzodiazepines
Neuroleptics
Botulinum Toxin Injections
Dystonia
Chorea
References
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