Читать книгу Current Concepts in Movement Disorder Management - Группа авторов - Страница 66

Apomorphine is a dopaminergic D₁/D₂ receptor agonist with a short half-life of nearly 45 min. Apomorphine injections via Penject device administration are effective for a rapid relief of a sudden “off” fluctuation during the day and nighttime. Continuous infusion can be carried out by an apomorphine pump, usually delivered for 12–16 h of the day. One of the main side effects related to the infusion system are skin reactions, resulting in the formation of small nodules [8].