Читать книгу Current Concepts in Movement Disorder Management - Группа авторов - Страница 71

Although the efficacy of clozapine has been documented in reducing limb tremor, it should be used as second-line treatment due to the well-known risk of important adverse events (such as agranulocytosis and cardiac toxicity). There are insufficient or conflicting data regarding the use of olanzapine and quetiapine in the treatment of limb tremor in ET [18–20].

Mirtazapine, a specific noradrenergic and serotoninergic antidepressant has been shown to be effective in reducing tremor of patients with ET in a few case series [20].