Читать книгу Vitamin D in Clinical Medicine - Группа авторов - Страница 37

1Bikle DD: Vitamin D: newly discovered actions require reconsideration of physiologic requirements. Trends Endocrinol Metab 2010;21:375–384.

2Wagner D, Hanwell HE, Schnabl K, Yazdanpanah M, Kimball S, Fu L, et al: The ratio of serum 24,25-dihydroxyvitamin D(3) to 25-hydroxyvitamin D(3) is predictive of 25-hydroxyvitamin D(3) response to vitamin D(3) supplementation. J Steroid Biochem Mol Biol 2011;126:72–77.

3Bikle DD, Gee E: Free, and not total, 1,25-dihydroxyvitamin D regulates 25-hydroxyvitamin D metabolism by keratinocytes. Endocrinology 1989;124:649–654.

4Holick MF, MacLaughlin JA, Clark MB, Holick SA, Potts JT Jr, Anderson RR, et al: Photosynthesis of previtamin D3 in human skin and the physiologic consequences. Science 1980;210:203–205.

5Webb AR, DeCosta BR, Holick MF: Sunlight regulates the cutaneous production of vitamin D3 by causing its photodegradation. J Clin Endocrinol Metab 1989;68:882–887.

6Houghton LA, Vieth R: The case against ergocalciferol (vitamin D2) as a vitamin supplement. Am J Clin Nutr 2006;84:694–697.

7Hollis BW: Comparison of equilibrium and disequilibrium assay conditions for ergocalciferol, cholecalciferol and their major metabolites. J Steroid Biochem 1984;21:81–86.

8Horst RL, Reinhardt TA, Ramberg CF, Koszewski NJ, Napoli JL: 24-Hydroxylation of 1,25-dihydroxyergocalciferol. An unambiguous deactivation process. J Biol Chem 1986;261:9250–9256.

9Zhu JG, Ochalek JT, Kaufmann M, Jones G, Deluca HF: CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo. Proc Natl Acad Sci U S A 2013;110:15650–15655.

10Moghadasian MH: Cerebrotendinous xanthomatosis: clinical course, genotypes and metabolic backgrounds. Clin Invest Med 2004;27:42–50.

11Cheng JB, Motola DL, Mangelsdorf DJ, Russell DW: De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilase. J Biol Chem 2003;278:38084–38093.

12Cheng JB, Levine MA, Bell NH, Mangelsdorf DJ, Russell DW: Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase. Proc Natl Acad Sci U S A 2004;101:7711–7715.

13Bikle D: Extra Renal Synthesis of 1,25-Dihydroxyvitamin D and its Health Implications; in Holick M (ed): Vitamin D: Physiology, Molecular Biology, and Clinical Applications. Humana Press 2010, pp 277–295.

14Bikle DD, Rasmussen H: The ionic control of 1,25-dihydroxyvitamin D3 production in isolated chick renal tubules. J Clin Invest 1975;55:292–298.

15Bikle DD, Murphy EW, Rasmussen H: The ionic control of 1,25-dihydroxyvitamin D3 synthesis in isolated chick renal mitochondria. The role of calcium as influenced by inorganic phosphate and hydrogen-ion. J Clin Invest 1975;55:299–304.

16Bikle DD: Extra renal synthesis of 1,25 dihydroxyvitamin D and its Health Implications. Clin Rev Bone Min Metab 2009;7:114–125.

17Bikle DD, Pillai S, Gee E, Hincenbergs M: Tumor necrosis factor-alpha regulation of 1,25-dihydroxyvitamin D production by human keratinocytes. Endocrinology 1991;129:33–38.

18Bikle DD, Pillai S, Gee E, Hincenbergs M: Regulation of 1,25-dihydroxyvitamin D production in human keratinocytes by interferon-gamma. Endocrinology 1989;124:655–660.

19Bikle DD, Nemanic MK, Gee E, Elias P: 1,25-Dihydroxyvitamin D3 production by human keratinocytes. Kinetics and regulation. J Clin Invest 1986;78:557–566.

20Gyetko MR, Hsu CH, Wilkinson CC, Patel S, Young E: Monocyte 1 alpha-hydroxylase regulation: induction by inflammatory cytokines and suppression by dexamethasone and uremia toxin. J Leukoc Biol 1993;54:17–22.

21St-Arnaud R, Messerlian S, Moir JM, Omdahl JL, Glorieux FH: The 25-hydroxyvitamin D 1-alpha-hydroxylase gene maps to the pseudovitamin D-deficiency rickets (PDDR) disease locus. J Bone Min Res 1997;12:1552–1559.

22Adams JS, Gacad MA: Characterization of 1 alpha-hydroxylation of vitamin D3 sterols by cultured alveolar macrophages from patients with sarcoidosis. J Exp Med 1985;161:755–765.

23Jones G, Prosser DE, Kaufmann M: 25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D. Arch Biochem Biophys 2012;523:9–18.

24Sakaki T, Sawada N, Komai K, Shiozawa S, Yamada S, Yamamoto K, et al: Dual metabolic pathway of 25-hydroxyvitamin D3 catalyzed by human CYP24. Eur J Biochem 2000;267:6158–6165.

25Prosser DE, Kaufmann M, O’Leary B, Byford V, Jones G: Single A326G mutation converts human CYP24A1 from 25-OH-D3–24-hydroxylase into -23-hydroxylase, generating 1alpha,25-(OH)2D3–26,23-lactone. Proc Natl Acad Sci U S A 2007;104:12673–12678.

26Plachot JJ, Du Bois MB, Halpern S, Cournot-Witmer G, Garabedian M, Balsan S: In vitro action of 1,25-dihydroxycholecalciferol and 24,25- dihydroxycholecalciferol on matrix organization and mineral distribution in rabbit growth plate. Metab Bone Dis Relat Res 1982;4:135–142.

27Schlingmann KP, Kaufmann M, Weber S, Irwin A, Goos C, John U, et al: Mutations in CYP24A1 and idiopathic infantile hypercalcemia. N Eng J Med 2011;365:410–421.

28O’Keeffe DT, Tebben PJ, Kumar R, Singh RJ, Wu Y, Wermers RA: Clinical and biochemical phenotypes of adults with monoallelic and biallelic CYP24A1 mutations: evidence of gene dose effect. Osteoporosis Int 2016;27:3121–3125.

29Armbrecht HJ, Hodam TL, Boltz MA, Partridge NC, Brown AJ, Kumar VB: Induction of the vitamin D 24-hydroxylase (CYP24) by 1,25-dihydroxyvitamin D3 is regulated by parathyroid hormone in UMR106 osteoblastic cells. Endocrinology 1998;139:3375–3381.

30Reddy GS, Muralidharan KR, Okamura WH, Tserng KY, McLane JA: Metabolism of 1alpha,25-dihydroxyvitamin D(3) and its C-3 epimer 1alpha,25-dihydroxy-3-epi-vitamin D(3) in neonatal human keratinocytes. Steroids 2001;66:441–450.

31Bailey D, Veljkovic K, Yazdanpanah M, Adeli K: Analytical measurement and clinical relevance of vitamin D(3) C3-epimer. Clin Biochem 2013;46:190–196.

32Kamao M, Tatematsu S, Hatakeyama S, Sakaki T, Sawada N, Inouye K, et al: C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation. J Biol Chem 2004;279:15897–15907.

33Brown AJ, Ritter C, Slatopolsky E, Muralidharan KR, Okamura WH, Reddy GS: 1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion. J Cell Biochem 1999;73:106–113.

34Carter GD, Jones JC, Shannon J, Williams EL, Jones G, Kaufmann M, et al: 25-Hydroxyvitamin D assays: potential interference from other circulating vitamin D metabolites. J Steroid Biochem Mol Biol 2015;164:134–138.

35Slominski AT, Janjetovic Z, Fuller BE, Zmijewski MA, Tuckey RC, Nguyen MN, et al: Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity. PloS One 2010;5:e9907.

36Byrdwell WC, Devries J, Exler J, Harnly JM, Holden JM, Holick MF, et al: Analyzing vitamin D in foods and supplements: methodologic challenges. Am J Clin Nutr 2008;88:554S-557S.

37Cai SS, Syage JA: Comparison of atmospheric pressure photoionization, atmospheric pressure chemical ionization, and electrospray ionization mass spectrometry for analysis of lipids. Anal Chem 2006;78:1191–1199.

38Adamec J, Jannasch A, Huang J, Hohman E, Fleet JC, Peacock M, et al: Development and optimization of an LC-MS/MS-based method for simultaneous quantification of vitamin D2, vitamin D3, 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3. J Sep Sci 2011;34:11–20.

39Singh RJ: Are clinical laboratories prepared for accurate testing of 25-hydroxy vitamin D? Clin Chem 2008;54:221–223.

40Muller MJ, Volmer DA: Mass spectrometric profiling of vitamin D metabolites beyond 25-hydroxyvitamin D. Clin Chem 2015;61:1033–1048.

41Haddad JG, Chyu KJ: Competitive protein-binding radioassay for 25-hydroxycholecalciferol. J Clin Endocrinol Metab 1971;33:992–995.

42Hummer L, Nilas L, Tjellesen L, Christiansen C: A selective and simplified radioimmunoassay of 25-hydroxyvitamin D3. Scand J Clin Lab Invest 1984;44:163–167.

43Bouillon R, Van Herck E, Jans I, Tan BK, Van Baelen H, De Moor P: Two direct (nonchromatographic) assays for 25-hydroxyvitamin D. Clin Chem 1984;30:1731–1736.

44Granado Lorencio F, Blanco-Navarro I, Perez-Sacrsitan B: Critical evaluation of assays for vitamin D status. Curr Opin Clin Nutr Metab Care 2013;16:734–740.

45Farrell CJ, Herrmann M: Determination of vitamin D and its metabolites. Best Pract Res Clin Endocrinol Metab 2013;27:675–688.

46Heijboer AC, Blankenstein MA, Kema IP, Buijs MM: Accuracy of 6 routine 25-hydroxyvitamin D assays: influence of vitamin D binding protein concentration. Clin Chem 2012;58:543–548.

47Farrell CJ, Martin S, McWhinney B, Straub I, Williams P, Herrmann M: State-of-the-art vitamin D assays: a comparison of automated immunoassays with liquid chromatographytandem mass spectrometry methods. Clin Chem 2012;58:531–542.

48Cashman KD, Kiely M, Kinsella M, Durazo-Arvizu RA, Tian L, Zhang Y, et al: Evaluation of Vitamin D Standardization Program protocols for standardizing serum 25-hydroxyvitamin D data: a case study of the program’s potential for national nutrition and health surveys. Am J Clin Nutr 2013;97:1235–1242.

49Jones G, DeLuca HF. High-pressure liquid chromatography: separation of the metabolites of vitamins D2 and D3 on small-particle silica columns. J Lipid Res 1975;16:448–453.

50Wootton AM: Improving the measurement of 25-hydroxyvitamin D. Clin Biochem Rev 2005;26:33–36.

51Bedner M, Phinney KW: Development and comparison of three liquid chromatography-atmospheric pressure chemical ionization/mass spectrometry methods for determining vitamin D metabolites in human serum. J Chromatogr A 2012;1240:132–139.

52Bailey D, Veljkovic K, Yazdanpanah M, Adeli K: Analytical measurement and clinical relevance of vitamin D(3) C3-epimer. Clin Biochem 2013;46:190–196.

53Herrmann M, Harwood T, Gaston-Parry O, Kouzios D, Wong T, Lih A, et al: A new quantitative LC tandem mass spectrometry assay for serum 25-hydroxy vitamin D. Steroids 2010;75:1106–1112.

54Higashi T, Shibayama Y, Fuji M, Shimada K: Liquid chromatography-tandem mass spectrometric method for the determination of salivary 25-hydroxyvitamin D3: a noninvasive tool for the assessment of vitamin D status. Anal Bioanal Chem 2008;391:229–238.

55Van Eeckhaut A, Lanckmans K, Sarre S, Smolders I, Michotte Y: Validation of bioanalytical LC-MS/MS assays: evaluation of matrix effects. J Chromatogr B Analyt Technol Biomed Life Sci 2009;877:2198–2207.

56Shah I, James R, Barker J, Petroczi A, Naughton DP: Misleading measures in Vitamin D analysis: a novel LC-MS/MS assay to account for epimers and isobars. Nutr J 2011;10:46.

57Maunsell Z, Wright DJ, Rainbow SJ: Routine isotope-dilution liquid chromatography-tandem mass spectrometry assay for simultaneous measurement of the 25-hydroxy metabolites of vitamins D2 and D3. Clin Chem 2005;51:1683–1690.

58Brumbaugh PF, Haussler DH, Bressler R, Haussler MR: Radioreceptor assay for 1 alpha,25-dihydroxyvitamin D3. Science 1974;183:1089–1091.

59Reinhardt TA, Horst RL, Orf JW, Hollis BW: A microassay for 1,25-dihydroxyvitamin D not requiring high performance liquid chromatography: application to clinical studies. J Clin Endocrinol Metab 1984;58:91–98.

60Hollis BW, Kamerud JQ, Kurkowski A, Beaulieu J, Napoli JL: Quantification of circulating 1,25-dihydroxyvitamin D by radioimmunoassay with 125I-labeled tracer. Clin Chem 1996;42:586–592.

61Seiden-Long I, Vieth R: Evaluation of a 1,25-dihydroxyvitamin D enzyme immunoassay. Clin Chem 2007;53:1104–1108.

62Valcour A, Zierold C, Podgorski AL, Olson GT, Wall JV, DeLuca HF, et al: A novel, fully-automated, chemiluminescent assay for the detection of 1,25-dihydroxyvitamin D in biological samples. J Steroid Biochem Mol Biol 2016;164:120–126.

63Strathmann FG, Laha TJ, Hoofnagle AN: Quantification of 1alpha,25-dihydroxy vitamin D by immunoextraction and liquid chromatography-tandem mass spectrometry. Clin Chem 2011;57:1279–1285.

64Aronov PA, Hall LM, Dettmer K, Stephensen CB, Hammock BD: Metabolic profiling of major vitamin D metabolites using Diels-Alder derivatization and ultra-performance liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem 2008;391:1917–1930.

65Kissmeyer AM, Sonne K: Sensitive analysis of 1alpha,25-dihydroxyvitamin D3 in biological fluids by liquid chromatography-tandem mass spectrometry. J Chromatogr A 2001;935:93–103.

66Casetta B, Jans I, Billen J, Vanderschueren D, Bouillon R: Development of a method for the quantification of 1alpha,25(OH)2-vitamin D3 in serum by liquid chromatography tandem mass spectrometry without derivatization. Eur J Mass Spectrom (Chichester) 2010;16:81–89.

67Singh RJ, Taylor RL, Reddy GS, Grebe SK: C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status. J Clin Endocrinol Metab 2006;91:3055–3061.

68Wang Z, Senn T, Kalhorn T, Zheng XE, Zheng S, Davis CL, et al: Simultaneous measurement of plasma vitamin D(3) metabolites, including 4beta,25-dihydroxyvitamin D(3), using liquid chromatography-tandem mass spectrometry. Anal Biochem 2011;418:126–133.

69Cashman KD, Hayes A, Galvin K, Merkel J, Jones G, Kaufmann M, et al: Significance of serum 24,25-dihydroxyvitamin D in the assessment of vitamin D status: a double-edged sword? Clin Chem 2015;61:636–645.

70Duan X, Weinstock-Guttman B, Wang H, Bang E, Li J, Ramanathan M, et al: Ultrasensitive quantification of serum vitamin D metabolites using selective solid-phase extraction coupled to microflow liquid chromatography and isotope-dilution mass spectrometry. Anal Chem 2010;82:2488–2497.

71Higashi T, Sakajiri K, Shimada K: Analysis of C-3 epimerization in (24R)-24,25-dihydroxyvitamin D3 catalyzed by hydroxysteroid dehydrogenase. J Pharm Biomed Anal 2004;36:429–436.

72Tanaka Y, Frank H, DeLuca HF, Koizumi N, Ikekawa N: Importance of the stereochemical position of the 24-hydroxyl to biological activity of 24-hydroxyvitamin D3. Biochemistry 1975;14:3293–3296.

73Burild A, Frandsen HL, Jakobsen J: Simultaneous quantification of vitamin D(3), 25-hydroxyvitamin D(3) and 24,25-dihydroxyvitamin D(3) in human serum by LC-MS/MS. Scand J Clin Lab Invest 2014;74:418–423.

74Ogawa S, Ooki S, Shinoda K, Higashi T: Analysis of urinary vitamin D(3) metabolites by liquid chromatography/tandem mass spectrometry with ESI-enhancing and stable isotope-coded derivatization. Anal Bioanal Chem 2014;406:6647–6654.

75Shah I, Petroczi A, Naughton DP: Method for simultaneous analysis of eight analogues of vitamin D using liquid chromatography tandem mass spectrometry. Chem Cent J 2012;6:112.

76Bikle DD, Halloran BP, Gee E, Ryzen E, Haddad JG: Free 25-hydroxyvitamin D levels are normal in subjects with liver disease and reduced total 25-hydroxyvitamin D levels. J Clin Invest 1986;78:748–752.

77Bikle DD, Gee E, Halloran B, Haddad JG: Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease. J Clin Invest 1984;74:1966–1971.

78Lai JC, Bikle DD, Lizaola B, Hayssen H, Terrault NA, Schwartz JB: Total 25(OH) vitamin D, free 25(OH) vitamin D and markers of bone turnover in cirrhotics with and without synthetic dysfunction. Liver Int 2015;35:2294–2300.

79Bikle DD, Siiteri PK, Ryzen E, Haddad JG: Serum protein binding of 1,25-dihydroxyvitamin D: a reevaluation by direct measurement of free metabolite levels. J Clin Endocrinol Metab 1985;61:969–975.

80Bikle DD, Gee E, Halloran B, Kowalski MA, Ryzen E, Haddad JG: Assessment of the free fraction of 25-hydroxyvitamin D in serum and its regulation by albumin and the vitamin D-binding protein. J Clin Endocrinol Metab 1986;63:954–959.

81Boutin B, Galbraith RM, Arnaud P: Comparative affinity of the major genetic variants of human group-specific component (vitamin D-binding protein) for 25-(OH) vitamin D. J Steroid Biochem 1989;32:59–63.

82Nielson CM, Jones KS, Chun RF, Jacobs JM, Wang Y, Hewison M, et al: Free 25-hydroxyvitamin D: impact of vitamin D binding protein assays on racialgenotypic associations. J Clin Endocrinol Metab 2016;101:2226–2234.

83Powe CE, Evans MK, Wenger J, Zonderman AB, Berg AH, Nalls M, et al: Vitamin D-binding protein and vitamin D status of black Americans and white Americans. N Engl J Med 2013;369:1991–2000.

84Denburg MR, Hoofnagle AN, Sayed S, Gupta J, de Boer IH, Appel LJ, et al: Comparison of two ELISA methods and mass spectrometry for measurement of vitamin D-binding protein: implications for the assessment of bioavailable vitamin D concentrations across genotypes. J Bone Min Res 2016;31:1128–1136.

85Schwartz JB, Lai J, Lizaola B, Kane L, Markova S, Weyland P, et al: A comparison of measured and calculated free 25(OH) vitamin D levels in clinical populations. J Clin Endocrinol Metab 2014;99:1631–1637.

Daniel D. Bikle, MD, PhD

VA Medical Center and University of California San Francisco

1700 Owens St., Rm 373

San Francisco, CA 94158 (USA)

E-Mail daniel.bikle@ucsf.edu