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Welcome to volume 6 of Translational Research in Biomedicine, a monograph series dedicated to the dissemination of seminal information in contemporary biomedicine with a translational orientation.

This volume is designed to be a comprehensive reference for shockwave medicine, a relatively new clinical specialty in modern medicine. Originally established as the gold standard for the disintegration of kidney stones, Extracorporeal Shockwave Therapy (ESWT) has progressively evolved to a regenerative treatment modality, and is currently indicated for musculoskeletal disorders and nonskeletal diseases that include ischemic heart disease, diabetic foot ulcers, acute or chronic wounds, and burn lesions. Authored by a panel of international experts and in the spirit of translational medicine, this volume provides a succinct summary of the history and principles of ESWT, the documentations that substantiate the launch of this new clinical specialty, the myriad of physical and cellular or molecular mechanisms that underpin the effects of shockwave, and the future prospects and directions of ESWT.

I wish to express my deep appreciation to Professors Ching-Jen Wang, Wolfgang Schaden, and Jih-Yang Ko, who have taken time from their heavy clinical duties and research endeavors to make this timely volume on “Shockwave Medicine” a reality. I am indebted to the generous patronage of Chang Gung Medical Foundation, Taiwan, which reduces substantially the increasing financial constraints on scientific publication, and allows us to concentrate on publishing timely and crucial themes in translational medicine. I also wish to acknowledge the capable hands of Freddy Brian and Angela Hefti at S. Karger AG during the development and production of this volume. Last but not least, the publication of Translational Research in Biomedicine would not have been possible without the foresight, enthusiasm, and whole-hearted support of my dear friend, Dr. Thomas Karger.

Samuel H.H. Chan, Kaohsiung

Series Editor