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The OPALINE cohort was supported by grants of the Regional Council of Burgundy, of IFR92, of PRNH-INRA-INSERM, and of the “ANR — The French National Research Agency” under the “Programme National de Recherche en Alimentation et nutrition humaine”, project “ANR-06-PNRA-028, OPALINE”; and of Blédina, Nestlé, Symrise, Cedus and Valrhona; labelled by Vitagora^®. S.N. received stipend from Nestlé Nutrition Insitute for participation in the 91st NNI workshop. Other authors have no financial relationship to disclose.