Читать книгу The Esophagus - Группа авторов - Страница 44

Trazodone is another early pharmacologic agent that was previously investigated in a six‐week double‐blind, randomized placebo‐controlled trial in 29 patients with esophageal symptoms and contraction abnormalities. In this trial, 15 patients treated with trazodone 100–150 mg daily showed a significantly greater global improvement (p = 0.02) with less residual distress over their esophageal symptoms (p = 0.03) [97].