Читать книгу The Esophagus - Группа авторов - Страница 49

Keefe et al. suggested a potential synergist effect between non‐pharmacologic and pharmacologic treatments through coping skills training (CST) among patients with NCCP randomized into four groups: CST plus sertraline 50–200 mg daily, CST plus placebo, sertraline alone, or placebo alone [93]. Compared to placebo, CST plus sertraline, CST plus placebo, and sertraline alone all resulted in reductions of reported pain intensity and unpleasantness (p < 0.001); however, only those randomized to CST plus sertraline had a reduction in reported pain catastrophizing (p = 0.02) [93].