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Distal esophageal spasm

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Distal (or diffuse) esophageal spasm (DES) is a rare motility disorder with an annual incidence of 1 per 100,000 and a prevalence of nearly 2% [142, 143]. The characteristic findings on HRM are premature contractions in ≥20% of swallows in conjunction with normal relaxation of the LES [124]. On HRM, a premature contraction is defined as a swallow with a distal latency of less than 4.5 seconds. More focused and expansive discussion can be found in Chapter 15.

The Esophagus

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