Читать книгу Bovine Reproduction - Группа авторов - Страница 56

Testosterone, follicle stimulating hormone (FSH), and luteinizing hormone (LH) are the main hormones required for spermatogenesis. Deficiency of these hormones causes germ cell apoptosis, while the administration of these suppresses apoptosis. Thus, these hormones are the survival factors required by germ cells. Under testosterone deficiency, round spermatids do not transition to elongated spermatids as the spermatids lose their attachment to Sertoli cells. FSH mainly acts indirectly through Sertoli cells. FSH has been linked to early stages in spermatogenesis, mainly spermatocytogenesis and meiosis, while testosterone is linked to later stages of spermatogenesis, mainly in spermatid differentiation and in potentiating the effect of FSH.