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Prevention

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For patients with diabetes undergoing ART, tight glycemic control is associated with normal ovarian response, fertilization and cleavage rates and pre‐embryonic development. Preconception counseling for good glycemic control is the basis for a good pregnancy outcome. Optimal BMI maintenance is required for better glycemic control. In patients with diabetes, prophylactic antibiotics during oocyte retrieval should be considered to reduce the risk of infection. Thrombo‐embolic risk assessment should be conducted, and appropriate thrombo‐prophylaxis instituted where indicated.

In men with diabetes, androgen status should be checked if they have symptoms of hypogonadism or if they are taking statins. Good glycemic control and optimal BMI are required for maintaining normal serum testosterone levels and semen parameters. Those with ED should be considered for a trial with phosphodiesterase inhibitors and advised to arrange a backup storage of frozen sperm in case they fail to produce sperm on the day of oocyte retrieval, or alternatively oocytes could be frozen if there were no sperm.

Assisted Reproduction Techniques

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