Читать книгу Assisted Reproduction Techniques - Группа авторов - Страница 120

The management of women with thyroid disease preconceptually and during pregnancy is a clinical area that is advancing rapidly. Recommendations are being refined as new evidence continues to emerge. Several controversies, including those surrounding the universal screening of pregnant women for thyroid disease, thresholds at which treatment should be commenced in newly diagnosed subclinical disease and whether to treat euthyroid thyroid peroxidase (TPO) antibody positive women, remain unresolved even after results have emerged from recently completed clinical trials. Updated clinical guidelines by different professional bodies have been published but the consensus opinions expressed are not identical [1,2]. Thus, there are differences in the specific management strategies adopted by various centers, but the general basic principles are broadly similar. It should also be noted that reference ranges for thyroid function tests vary according to the laboratory assay, ethnicity of the population and stage of pregnancy.