Читать книгу Assisted Reproduction Techniques - Группа авторов - Страница 119

Shiao‐yng Chan

Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

Case History 1: A 35‐year‐old woman with unexplained infertility is about to undergo IVF treatment. She has been diagnosed with hypothyroidism 2 years ago. She has maintained normal thyroid function test results with levothyroxine 100 μg/day for the past 18 months and has been clinically euthyroid. Her most recent test showed a thyroid stimulating hormone (TSH) level of 3.8 mU/L (normal range: 0.4–4.2 mU/L) and a free thyroxine (T4) level of 12.2 pmol/L (9.5–20 pmol/L).

Case History 2: A 26‐year‐old woman was diagnosed with Graves’ disease 6 months following the delivery of her only child 4 years ago. After 2 years of carbimazole treatment her disease became quiescent but recurred 6 months ago. She is currently on carbimazole 30 mg/day and is clinically euthyroid with a small soft diffuse palpable goiter. She has been with a new partner for the last 2 years and would like to proceed with ICSI for male factor infertility. Thyroid function tests performed within the last month showed a TSH level of 0.03 mU/L (0.4–4.2 mU/L), free T4 of 18 pmol/L (9–20 pmol/L) and free T3 of 6 pmol/L (3.5–6.8 pmol/L).