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The Research Domain Criteria (RDoC) Initiative

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In 2009, the National Institute of Mental Health (NIMH) launched the RDoC initiative (Insel et al., 2010). This was part of the Institute’s strategic plan to begin developing a dimensional system of psychopathology, ultimately aiming to revamp the traditional categorical models used in the field (i.e., DSM and ICD). The RDoC initiative is not a classification system per se. It is a systematic framework or template for guiding and conducting psychopathological research from a “bottom up” dimensional approach (Kozak & Cuthbert, 2016). Thus, much of the research conducted as part of RDoC examines transdiagnostic symptoms or causal factors shared across many forms of psychopathology. For example, research conducted as part of the RDoC initiative might not look at the symptom or surface level differences between different anxiety disorders defined by the DSM. Instead, studies might look at a certain symptom typically associated with anxiety disorders, such as fear, and study the neurobiological mechanisms, and endophenotypes, underlying fear so that we can better understand how or why a person might develop this specific symptom (see Figure 1.2).

Developmental Psychopathology

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