Читать книгу Sarcopenia - Группа авторов - Страница 74

Systematic reviews on prospective studies of people aged 60 years and over as well as individual population studies have shown that sarcopenia increases the odds ratio of mortality between 1.6 and 3.6 [1–3], and that the effect was higher in people aged 79 years or older [1]. Individual constituent definition of sarcopenia, such as grip strength, and body composition among community‐living older people aged 65 years and over also predicted all‐cause mortality [4, 5], while grip strength and other physical performance measures in mid‐life predicted late‐life mortality [6–8].

With respect to secondary sarcopenia in the clinical setting, other than increased mortality (with odds ratio much higher than those for community‐living older people), depleted muscle mass is also associated with infection, increased duration of mechanical ventilation, longer hospitalization, readmission rates, and rehabilitation needs [9]. Worse outcomes are observed among patients with liver failure.