Читать книгу Blackwell's Five-Minute Veterinary Consult Clinical Companion - Группа авторов - Страница 54

 Intravenous fat emulsion/intravenous lipid emulsion (Intralipid, others):Used in human and small animal medicine to reverse the signs associated with several toxins such as lidocaine, mepivacaine, ivermectin, moxidectin, beta blockers, calcium channel blockers and others.Has been used successfully in a miniature horse and foals with ivermectin toxicosis.There is no equine dose available. Information and dosage have been extrapolated from small animal and human data.Dosage: using a 20% solution, inject 1.5 mL/kg through a jugular catheter over 5–15 minutes; follow with a CRI of 0.25 mL/kg/min over 1–2 h. Repeat in several hours if signs of toxicosis return. Check serum for lipemia prior to giving additional doses and do not administer if lipemia is present.

 Methylene blue (generic, various):Infrequently used to treat methemoglobinemia formed secondary to oxidative agents such as hydroxyurea, nitrates, and phenols.Dose: 1% solution, 4.4 mg/kg IV; repeat dose in 15–30 minutes if no response.

 Neostigmine:Neostigmine (AChE inhibitor) has been used in animals and humans to successfully reverse Micrurus venom‐induced cholinesterase actions.Dose: 0.02 mg/kg SC or IV.