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Primary Lymphoid Organs

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The primary lymphoid organs in the mouse are the bone marrow for the antigen‐independent generation of B cells and the thymus for T cells. The general assessment of bone marrow is described above. Microscopy of routinely stained sections of bone marrow does not provide specific information about the development of B cells. This requires isolation of bone marrow cells followed by labeling with appropriate reagents and analysis by flow cytometry.

Pathology of Genetically Engineered and Other Mutant Mice

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