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Bone Healing and Radiation Therapy

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Eisenschenk et al. (2006) showed a significant worsening in bone healing and stability after pre‐ and post‐operative radiation therapy to the wound bed and vascularized bone grafts (Eisenschenk et al. 2006). Such complications can lead to an increased chance of delayed unions, non‐unions, and fracture. Similarly, in a canine study, pre‐operative irradiation significantly impaired allograft incorporation in a limb‐salvage model as determined by radiographic healing scores, histomorphometry, and frequency of non‐unions (Ehrhart et al. 2005).

Veterinary Surgical Oncology

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