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Calcineurin inhibitors

Оглавление

The topical calcineurin inhibitors (CNIs) have anti‐inflammatory and immunomodulatory actions. They inhibit calcineurin phosphatase, resulting in the reduction in T‐cell activation and cytokine production. They have been used in several vulval dermatoses [14], but are not as effective as potent topical steroids in lichen sclerosus and lichen planus.

Ridley's The Vulva

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