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1.2.1 Micro‐XRF

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XRF is a bulk technique with the analysis range varying from several millimeters to several centimeters. Inhomogeneous samples compacted into a pellet form and thereby make it little time consuming. Also it requires a large amount of sample material for the analysis. Many advancements have been made in the field of X‐ray optics that gave rise to originate to narrow X‐ray beams (1 mm to 10 μm). Such developments allow even a solo microscopic particle to be discretely analyzed for an explicit elemental image of high spatial resolution.

XRF [7] is based on an energy‐dispersive detection system. For the generation of precise and accurate elemental images consisting of thousands of pixels, a fast acquisition is needed at each and every pixel position. When using a simple WDXRF spectrometer, the scanning procedure is time consuming and does not support the imaging applications as provided by XRF. XRF has broad range of research applications including geology, mineralogy, gemology, archaeology, motor engineering, electronics, pharmaceutics, environmental studies, and biomedicine.

X-Ray Fluorescence in Biological Sciences

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