Читать книгу Plant Nucleotide Metabolism - Hiroshi Ashihara - Страница 55

The second step of the de novo pathway is the ATP-dependent formation of glycineamide ribonucleotide (GAR) by the addition of glycine to PRA via an amide bond. This reaction is catalysed by glycineamide ribonucleotide synthetase (GARS, EC 6.3.4.13) (step 2, Figure 4.1, Reaction 2).

The enzymatic properties of GARS are not well characterized. However, fluctuation in its activity during growth of cultured carrot cells has been investigated and the highest level was found in the cell division phase (Ashihara and Nygaard 1989).