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The age, breed, sex, use, and value of a patient all are important considerations in the diagnosis and prognosis of many neurologic conditions. Several diseases are age‐dependent. Certain diseases are associated with breed (see Chapter 31). Only a few neurologic diseases depend upon sex. The uses to which animals are put can be associated with certain diseases, and this impacts considerably on the prognosis that accompanies the diagnosis. Because many large animals are kept for economic purposes, the value of the patient must always be kept in mind with respect to time spent on evaluation, cost of therapy, and future productivity; the survival and productivity of any herd mates must also be considered.