Читать книгу Applied Biostatistics for the Health Sciences - Richard J. Rossi - Страница 26

In the article “Randomized, double-blind, placebo-controlled trial of 2 dosages of sustained-release bupropion for adolescent smoking cessation” published in the Archives of Pediatric and Adolescent Medicine (Muramoto et al., 2007), the authors reported the results of a randomized controlled double-blind research study designed to investigate the efficacy of sustained release of bupropion hydrochloride for adolescent smoking cessation. This study consisted of n = 312 subjects recruited through media and community venues from March 1, 1999 to December 31, 2002, who were aged 14–17 years, smoked at least six cigarettes per day, had an exhaled carbon monoxide level of 10 ppm or greater, had at least two previous quit attempts, and had no other current major psychiatric diagnosis.