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1.3 Provision of analytical toxicology services

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If poisoning is suspected and appropriate biological samples have been obtained, the stages in processing analytical work can be divided into pre-analytical, analytical, and post-analytical phases (Table 1.3).

Table 1.3 Steps in undertaking an analytical toxicological investigation

Pre-analytical Obtain details of the current (suspected) poisoning episode, including any circumstantial evidence of poisoning, and the results of biochemical and haematological investigations, if any. Also obtain the patient's medical and occupational history, if available. Decide the priorities for the analysis
Analytical Perform the agreed analysis
Post-analytical Interpret the results in discussion with the physician looking after the patient or the pathologist. Perform additional analyses, if indicated, using either the original samples, or further samples from the patient. Save any unused or residual samples for possible future use
Fundamentals of Analytical Toxicology

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