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2.2.2 Clinical sample types

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Clinical samples can be divided into (i) blood and related fluids, (ii) body fluids other than blood, (iii) excretory fluids/residues, and (iv) other clinical specimens (Table 2.2). A range of additional specimens may be collected for toxicological purposes. Special precautions will be needed with unstable analytes. Most compounds measured in urine can be considered stable for at least a few hours at room temperature because the urine may already have been held at body temperature for some time before it was voided. Nevertheless, stability testing should be included in any method validation work.

Fundamentals of Analytical Toxicology

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