Читать книгу Fundamentals of Analytical Toxicology - Robin Whelpton - Страница 67

Liver is easily collected post-mortem and readily homogenized. It may contain large amounts of drugs and metabolites, and may be the primary specimen submitted for analysis if blood is not available. A portion (10–20 g) of unpreserved wet tissue should be collected. The sample should be taken from the right lobe, if possible, to reduce the risk of contamination with bile and because any diffusion of poison from the stomach is less likely than in the left lobe. An analysis may, in some cases, help to establish whether either acute, or chronic exposure has occurred, but sometimes the analysis can do little more than establish exposure in the absence of reliable information to aid in the interpretation of quantitative results (Section 22.3.2).