Читать книгу Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations - Sheila Annie Peters - Страница 38

At steady state, the rate of change in the amount of metabolite in the body is zero, making the left‐hand sides of Equations 1.50 and 1.54 equal zero. It follows that the amount and concentration of the metabolite in the body at steady state are:

(1.58)