Читать книгу Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations - Sheila Annie Peters - Страница 44
1.5.2 Functional Adaptation Processes
ОглавлениеOne of the perils of drug development is the occurrence of time‐dependent modulations in pharmacological activity upon repeat administration of certain drugs, arising from functional adaptation processes such as desensitization and sensitization.