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2 A REVIEW OF DRUG–DRUG INTERACTIONS CONTENTS

Оглавление

2.1 Introduction

2.2 Drug Interactions Mediated by Enzymes and Transporters at Various Sites

2.3 Factors Affecting DDI

2.4 In Vitro Methods to Evaluate Drug–Drug Interactions 2.4.1 Candidate Drug as a Potential Perpetrator 2.4.2 Candidate Drug as a Potential Victim of Inhibition

2.5 Sources of Uncertainty

2.6 Therapeutic Protein–Drug Interaction Keywords References

Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations

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