Читать книгу Open and Toroidal Electrophoresis - Tarso B. Ledur Kist - Страница 15

Neutral and non-ionizable solutes that are able to form hydrogen bonds tend to be soluble in water. Of course, solubility depends on the size of the molecule, the number of hydrogen bonds each molecule forms with water, the interaction energies of the solute molecules with themselves, and the entropy changes involved. If the number of hydrogen bonds is small and the solute molecules are large compared to the water molecules, then the solute tends to be expelled out from the bulk (interior) of the water by the water molecules. An exact prediction of solubility is given by the Gibbs free energy change (see Section 1.1.8).