Читать книгу Snyder and Champness Molecular Genetics of Bacteria - Tina M. Henkin - Страница 107

The nucleoid was described with respect to chromosome segregation above. Indeed, experiments in many of the model systems indicate that bacteria carefully coordinate the position of the chromosome in the cell. Through techniques in which individual positions in the chromosome can be localized in whole cells, it has been shown that genes are located in the chromosome in roughly the same order as one would presume by looking at the DNA sequence. A variety of techniques are providing insight into how the structure of the chromosome is maintained in the cell. The molecular mechanisms that maintain the chromosome structure remain a mystery, but specific systems are likely to exist to ensure that the chromosome is available for transcription, recombination, and other functions.