Читать книгу Snyder and Champness Molecular Genetics of Bacteria - Tina M. Henkin - Страница 93

Not only must the two daughter chromosomes be segregated after replication, they also must be segregated in such a way that each daughter cell gets only one of the two copies of the chromosome. Otherwise, one daughter cell would get two chromosomes and the other would be left with no chromosome and eventually would die. The apportionment of one daughter chromosome to each of the two daughter cells is called partitioning. Daughter cells that lack a chromosome after division are very rare, indicating that partitioning is a very efficient process in bacteria. Because of the importance of chromosome segregation, redundant mechanisms may have evolved to ensure that it occurs accurately. Indeed, many of the mechanisms that allow condensation of chromosomes can contribute to partitioning once the origin regions are located in the nascent daughter cells. While broad themes that describe partitioning across all bacteria have eluded our understanding, some important model systems are fairly well understood. In this section, we discuss what is known in the model bacteria.