Читать книгу Snyder and Champness Molecular Genetics of Bacteria - Tina M. Henkin - Страница 62

DNA ligases are enzymes that form phosphodiester bonds between the ends of separate presynthesized chains of DNA. This important function cannot be performed by any of the known DNA polymerases. During replication, ligase joins the 5′ phosphate at the end of one DNA chain to the 3′ hydroxyl at the end of another chain to make a longer, continuous chain (Figure 1.8).