Читать книгу Snyder and Champness Molecular Genetics of Bacteria - Tina M. Henkin - Страница 43

François Jacob and Jacques Monod published their operon model for the regulation of the lactose utilization genes of E. coli in 1961 as well. They proposed that a repressor blocks RNA synthesis on the lac genes unless the inducer, lactose, is bound to the repressor (see chapter 11). Their model has served to explain gene regulation in other systems, and the lac genes and regulatory system continue to be used in molecular genetic experiments, even in systems as far removed from bacteria as animal cells and viruses.